Preprint: Molecular surface chemistry defines nematode development, identity and behaviour

Kotowska, A. M., Hiramatsu, F., Alexander, M. R., Scurr, D. J., Lightfoot, J.W.# and Chauhan V. M.# (2024) BioRxiv  [article]

Kin-recognition and predation shape collective behaviours in the cannibalistic nematode Pristionchus pacificus.

Hiramatsu, F. and Lightfoot, J.W. (2023) PLoS Genetics. [article]

Divergent combinations of cis-regulatory elements control the evolution of phenotypic plasticity.

Dardiry, M., Eberhard. G., Witte, H., Rödelsperger, C., Lightfoot, J.W., and Sommer R. J. (2023) PLoS Biology. [article]

Evolution and diversity of TGF-β pathways are linked with novel developmental and behavioural traits.

Lo, W-S.,* Roca, M.,* Dardiry, M.,* Franco, K., Eberhardt, G., Witte, H., Hong, R., Sommer, R.J., Lightfoot, J.W. (2022) Molecular Biology and Evolution. [article]

Genomic integration of transgenes using UV irradiation in Pristionchus pacificus.

Eren. G. G., Roca. M., Han. Z., Lightfoot, J. W. (2022) MicroPublications Biology. [article]

Sex or cannibalism: polyphenism and kin recognition control social action strategies in nematodes. 

Lightfoot, J.W.,* Dardiry. M.,* Kalirad, A., Giaimo, S., Eberhardt, G., Witte, H., Wilecki, M., Roedelsperger, C., Traulsen, A., S., Sommer, R.J. (2021) Science Advances. [article]

Improving transgenesis efficiency and CRISPR-associated tools through codon optimization and native intron addition in pristionchus nematodes.

Han, Z., Lo, W-S., Lightfoot, J.W., Witte, H., Sun, S., Sommer, R.J. (2020) Genetics. [article]

Conserved nuclear hormone receptors controlling a novel plastic trait target fast-evolving genes expressed in a single cell.

Sieriebriennikov, B., Sun, S., Lightfoot, J.W., Witte, H., Moreno, E., Rödelsperger, C., Sommer, R.J. (2020) PLoS Genetics. [article]

Bacterial vitamin B12 production enhances nematode predatory behavior. 

Akduman, N., Lightfoot, J.W., Röseler, W., Witte, H., Lo, W-S., Rödelsperger, C., Sommer, R.J. (2020) ISME J. [article]

Cilia drive developmental plasticity and are essential for efficient prey detection in predatory nematodes. 

Moreno, E., Lightfoot, J. W., Lenuzzi, M., Sommer, R. J. (2019) Proc R Soc B. [article]

Small peptide-mediated self-recognition prevents cannibalism in predatory nematodes. 

Lightfoot, J.W., * Wilecki, M., * Rödelsperger, C., Moreno, E., Susoy, V., Witte, H., Sommer, R.J. (2019)

Science. [article] 

Regulation of hyperoxia-induced social behaviour in Pristionchus pacificus nematodes requires a novel cilia-mediated environmental input. 

Moreno, E., Sieriebriennikov, B., Witte, H., Rödelsperger, C., Lightfoot, J.W., Sommer, R.J. (2017) Sci rep. [article]

Assaying Predatory Feeding Behaviors in Pristionchus and Other Nematodes

Lightfoot J.W.,* Wilecki, M.,* Okumura, M., Sommer, R.J. (2016) J Vis Exp. [article]

Comparative transcriptomics of the nematode gut identifies global shifts in feeding mode and pathogen susceptibility. 

Lightfoot, J.W., Chauhan, V.M., Aylott, J.W., Rödelsperger, C. (2016) BMC Res Notes. [article]

Predatory feeding behaviour in Pristionchus nematodes is dependent on phenotypic plasticity and induced by serotonin. 

Lightfoot, J.W. *, Wilecki, M.,* Susoy, V., Sommer, R.J. (2015) J Exp Biol. (Cited as Wilecki and Lightfoot et al.) [article]

Other publications

Gao, J., Barroso, C., Zhang, P., Kim, H.M., Li, S., Labrador, L., Lightfoot, J., Gerashchenko, M.V., Labunskyy, V.M., Dong, M.Q., Martinez-Perez, E., Colaiácovo, M.P. (2016) Genes Dev. 2016 [article]

Kulkarni, A., Lightfoot, J.W., Streit, A. (2016) Chromosoma. 2016 [article]

Silva, N., Ferrandiz, N., Barroso, C., Tognetti, S., Lightfoot, J., Telecan, O., Encheva, V., Faull, P., Hanni, S., Furger, A., Snijders, A.P., Speck, C., Martinez-Perez, E. (2014) Dev Cell. 2014 [article]

Labrador, L., Barroso, C., Lightfoot, J., Müller-Reichert, T., Flibotte, S., Taylor, J., Moerman, D.G., Villeneuve, A.M., Martinez-Perez, E. (2013). PLoS Genet. 2013 [article]

Lightfoot, J., Testori, S., Barroso, C., Martinez-Perez E (2011). Curr. Biol. 2011 [article]

Martinez-Perez, E., Schvarzstein, M., Barroso, C., Lightfoot, J., Dernburg, A.F., Villeneuve, A.M. (2008) Genes Dev. 2008 [article]

Jackson, R.J., Elvers, K.T., Lee, L.J., Gidley, M.D., Wainwright, L.M., Lightfoot, J., Park, S.F., Poole, R.K. (2007) J. Bacteriol. 2007 [article]


Hedonic worms gorge on high-energy foods. 

Roca, M., and Lightfoot, J.W.,

Current Biology,  2023. 

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